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The Autonomic Nervous System and Cardiovascular Health: A Deep Dive

Feb 20, 2025

The autonomic nervous system (ANS) is a critical component of our body's regulatory framework, controlling involuntary functions such as heart rate, blood pressure, and digestion. Its impact on cardiovascular health is profound, making it an essential subject for anyone concerned with maintaining a healthy heart and circulatory system. Notwithstanding the fact that this platform focuses on pelvic floor health and fitness almost exclusively, the same sources of physiological dysfunction that affect the bladder and bowel also affect every other organ system. For this reason, I hope the reader will allow me a brief, well somewhat brief, departure from our normal routine. In today’s post we are discussing the impact of autonomic dysfunction on the cardiovascular system. Cardiovascular disease is the number one cause of death for both men and women. We often discuss the fact that bladder control is a fitness issue. The pelvic floor muscles provide regulatory feedback to the central nervous system elements that control how full the bladder feels and how likely the bladder is to empty without the owners consent. Here is the important point:

— The autonomic dysfunction that affects the cardiovascular system affects every other organ system as well. If you have a bladder control problem like overactive bladder (autonomic dysfunction) it is possible that it is also impacting your cardiovascular health.

Autonomic nervous system dysfunction is more common than many realize, and the prevalence increasing with age. Believe it or not autonomic nervous system dysfunction affects about 50% of adults. The impact of this dysfunction can be far-reaching, contributing to a reduced quality of life and increased mortality rates. For example, individuals with autonomic dysfunction have a higher risk of cardiovascular events, such as strokes and heart attacks, but also non-lethal medical problems like erectile dysfunction and overactive bladder. Clearly autonomic nervous system dysfunction significantly impacts quality of life and longevity.

So, when trying to help a patient with overactive bladder one should consider first principals. A good doctor should ask the question: “what is this patients bladder telling me about their overall health?" Having overactive bladder is a known risk factor for cardiovascular disease. Instead of treating just the bladder we should consider the whole patient and the implications of having generalized autonomic dysfunction.

As we age our autonomic nervous system becomes less regulated. This leads to several problems including:

1. MetabolicDysfunction(diabetes,inflammation)

  1. Hypertension

  2. Overactive Bladder

  3. Irritable Syndrome

  4. ErectileDysfunction

It is clear that metabolic dysfunction, chronic inflammation, and hypertension are risk factors for developing atherosclerosis, the vascular disease causing most heart attacks, strokes, and congestive heart failure. The problem is that most people are woefully unaware they are developing atherosclerosis until they experience an event, like a stroke or heart attack. Some indicators of autonomic dysregulation like hypertension get a great deal of attention. Others like erectile dysfunction and overactive bladder are seldom recognized as indicators of the same sort of generalized autonomic decline. So the question we need to ask is this: Is overactive bladder actually a risk factor for cardiovascular disease?

The answer is yes.

Overactive bladder (OAB) is increasingly recognized as a potential risk factor for cardiovascular disease (CVD), especially in older adults. Several mechanisms link the two conditions:

  • Epidemiological Studies: Studies have shown that individuals with OAB symptoms, particularly urgency and nocturia, have a higher prevalence of hypertension, stroke, and cardiovascular events.

  • Cardiovascular Mortality: Severe OAB symptoms have been linked to increased cardiovascular mortality, particularly in those with comorbidities. Comorbidities is a medical term for someone that has more than one medical condition.

    Implications:

    While OAB itself is not traditionally considered a direct cause of CVD, it can act as an indicator or amplifier of underlying risk factors. Managing OAB should be oriented by the understanding that it may be a symptom of more generalized autonomic dysregulation.

    Recognizing the symptoms of autonomic nervous system dysfunction is crucial for early intervention and management. Some of the key symptoms, other than overactive bladder, that can affect cardiovascular health include:

  • Orthostatic hypotension: A significant drop in blood pressure upon standing, causing dizziness, lightheadedness, and even fainting.

  • Resting tachycardia: An abnormally high heart rate while at rest, which can lead to increased cardiac workload and potential heart damage over time.

  • Exercise intolerance: Difficulty in maintaining physical activity levels due to fatigue and an inability to achieve an adequate heart rate response during exercise.

  • Palpitations: Sensations of rapid, fluttering, or pounding heartbeats, which can be distressing and indicate underlying heart rhythm problems.

  • Decreased heart rate variability: The variability in the time between heart beats is a marker for autonomic health. Higher heart rate variability is associated with better autonomic function. This can be measured by various wearable devices such as the Apple Watch.


    Fortunately, there are several steps individuals can take to improve autonomic dysfunction and support cardiovascular health:

  • Regular physical activity: Engaging in moderate-intensity exercise, such as brisk walking, swimming, or cycling, can enhance cardiovascular fitness and improve autonomic function.

  • Healthy diet: Consuming a balanced diet rich in fruits, vegetables, whole grains, and lean proteins can help maintain optimal blood pressure and heart function.

  • Stress management: Practicing relaxation techniques such as yoga, meditation, and deep breathing exercises can reduce sympathetic nervous system activity and promote parasympathetic balance.

  • Adequate hydration: Maintaining proper hydration levels supports blood volume and pressure, aiding in the prevention of orthostatic hypotension.

  • Medication management: For those with underlying conditions such as diabetes or hypertension, adhering to prescribed medications and regularly monitoring blood pressure and glucose levels is essential.